Our technology.

The power of molecular intelligence.

Molecular machine learning hidden within the simplicity of PCR.

 

Our PCRchitectur platform is a breakthrough technology that expands the capabilities of traditional qPCR, for simpler workflows and faster time to results. PCRchitectur enables highly multiplexed target interrogation and is compatible with existing qPCR instruments and off-the-shelf reagents.

 

Personalized patient treatment slowed down by legacy technologies.

Transcriptional signatures, or gene expression signatures, offer a modern approach to diagnosis of complex diseases. These signatures offer a powerful window into individual patient characteristics to inform personalised treatment, but translating them to the clinic has been hampered by traditional approaches.

Legacy approaches for measuring gene expression signatures were built for the lab, not the clinic. Running a dozen qPCR reactions in parallel? Limited throughput, poor reproducibility. Sequencing? Microarrays? High up-front and reagent costs, testing bottlenecks, specialized and laborious sample preparation, and sophisticated analysis needed for interpretation. The latest all-in-one device? Minimal flexibility, shallow market penetration, and questionable durability.

The PCRchitectur platform offers fast results with simple workflows which can be easily performed in clinical labs around the world.

The science under the hood.

Legacy technologies rely on measuring each RNA sequence one-by-one and then combining this information later. PCRchitectur couples measurement and interpretation into a single step…

The PCRchitectur platform combines the nuance of competitive PCR biology with the power of machine learning on the molecular level. The result is a platform compatible with existing clinical workflows, yielding a simple readout and ensuring that clinicians and patients obtain rapid and accurate results.

 

Key benefits of the PCRchitectur platform:

  • Usability & Access.

    Our smart PCR kits work with widely available qPCR machines, seamlessly integrating into biomedical labs around the world.

  • Faster & Cheaper.

    No need to rely on high-demand sequencers, complex bioinformatic analysis, or expensive reagents that compromise access to medical innovation. A PCRchitectur test delivers robust results when and where they’re needed.

  • Bespoke, versatile design.

    We can design a PCRchitectur specification for the majority of mRNA or miRNA signatures. Get in touch and let us transform your clinical data into a clinical test that supports patient outcomes.